Proceedings of an American Chemical Society Carbohydrate Division Symposium (Tohru Ueda Memorial Symposium), held in San Francisco, April 1992. Among the topics in 17 papers: lithiation chemistry of uridine derivatives access to a new anti-HIV-1 lead; approaches to novel isomeric nucleosides as anti

Due to the worldwide epidemic of acquired immunodeficiency syndrome (AIDS), the past ten years have witnessed a flurry of activity in the chemotherapy of viral diseases. Unprecedented scientific efforts have been made by scientists and clinicians to combat infections of human immunodeficiency virus (HIY), the causative agent. Looking back over the past ten years, we have made remarkable progress toward the treatment of the viral disease: isolation of HIV only two years after the identification of the disease, plus major strides in the areas of the molecular biology and virology of the...