Nucleosides and Nucleotides as Antitumor and Antiviral Agents

ISBN-13: 9780306445200 / Angielski / Twarda / 1993 / 336 str.

Chung K. Chu; D. C. Baker; C. K. Chu

Opis

Proceedings of an American Chemical Society Carbohydrate Division Symposium (Tohru Ueda Memorial Symposium), held in San Francisco, April 1992. Among the topics in 17 papers: lithiation chemistry of uridine derivatives access to a new anti-HIV-1 lead; approaches to novel isomeric nucleosides as anti

Spis treści

Design of New Types of Antitumor Nucleosides (A. Matsuda et al.). Lithiation Chemistry of Uridine Derivatives (H. Tanaka et al.). A Synthesis of 2'Fluoro and 3'FluoroSubstituted Purine Nucleosides via a Direct Approach (K.W. Pankiewicz, K.A. Wantanabe). Allenols Derived from Nucleic Acid Bases-A New Class of AntiHIV Agents (J. Zemlicka). StructureActivity Relationships among HIV Inhibatory, 4'Substituted Nucleosides (E.J. Prisbe et al.). Approaches to Novel Isomeric Nucleosides as Antiviral Agents (V. Nair). Carbocyclic 7Deazaguanosine Nucleosides as Antiviral Agents (S.W. Schneller et al.). Synthesis and Anticancer and Antiviral Activity of Certain Pyramidine Nucleoside Analogues (T.S. Lin, M.C. Liu). Stereocontrolled Routes for the Synthesis of AntiHIV and AntiHBV Nucleosides (J.W. Beach et al.). 5Substituted Arabinofuranosyluracil Nucleosides as Antiherpes Agents (H. Machida, S. Sakata). 6 additional articles. Index.