Thirty years have passed since somatostatin was discovered and its hormonal function defined 1,2]. The wide range of anatomical distribution and actions of somatostatin and its receptors stimulated intense scientific and clinical interest, and fostered extensive research into all aspects of its biology including regulation of its gene expression, processing of its precursor, biological and cellular actions relating to regulation cell secretion, motility and proliferation. The development of metabolically stable peptide analogs helped define its usefulness in the treatment of endocrine...
Thirty years have passed since somatostatin was discovered and its hormonal function defined 1,2]. The wide range of anatomical distribution and acti...