The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gene expression in living subjects is rapidly moving from the research laboratory into daily clinical settings. The interdisciplinary nature of the field mandates a constant dialogue among molecular and cellular biology, chemistry, physics, image analysis, and drug discovery to develop and translate promising approaches into reliable scientific applications and viable clinical diagnostic tools. Bringing together a select panel of...
The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gen...
At the end of the 20th century, a tremendous progress was made in biotechnology in its widest sense. This progress was largely possible as a result of joint efforts of top academic researchers in both pure fundamental sciences and applied research. The surplus value of such interdisciplinary approaches was clearly highlighted during the 9th European Congress on Biotechnology that was held in Brussels, Belgium (11-15 July, 1999). The present volume in the Focus on Biotechnology series, entiteld Physics and Chemistry Basis for Biotechnology contains selected presentations from this meeting, A...
At the end of the 20th century, a tremendous progress was made in biotechnology in its widest sense. This progress was largely possible as a result of...
At the end of the 20th century, a tremendous progress was made in biotechnology in its widest sense. This progress was largely possible as a result of joint efforts of top academic researchers in both pure fundamental sciences and applied research. The surplus value of such interdisciplinary approaches was clearly highlighted during the 9th European Congress on Biotechnology that was held in Brussels, Belgium (11-15 July, 1999). The present volume in the Focus on Biotechnology series, entiteld Physics and Chemistry Basis for Biotechnology contains selected presentations from this meeting, A...
At the end of the 20th century, a tremendous progress was made in biotechnology in its widest sense. This progress was largely possible as a result of...
Here, expert researchers in the field provide a comprehensive collection of experimental MRI protocols that can be used to non-invasively interrogate the healthy and diseased brain. The chapters are divided into general techniques, such as the measurement of relaxivity, magnetic resonance spectroscopy, and diffusion tensor imaging.
Here, expert researchers in the field provide a comprehensive collection of experimental MRI protocols that can be used to non-invasively interrogate ...
The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these imaging particles can be designed to fulfill specific requirements for applications across different imaging modalities. It presents, for the first time, a comprehensive interdisciplinary overview of the impact nanoparticles have on biomedical imaging and is a common central resource for researchers and teachers.
The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these...
This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic...
This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic parti...
Michael T. McMahon Jeff W. M. Bulte Assaf A. Gilad
Chemical exchange saturation transfer (CEST) imaging is a powerful magnetic resonance imaging (MRI) technique with unique contrast features. This technology enables the amplified detection of nM to mM concentrations of small molecules and macromolecules (including those involved in biologic pathways) through selective radio frequency labeling of rapidly exchanging protons present on the molecules of interest. Because this labeling is frequency dependent, CEST agents have advantages over the more established water relaxation based contrast agents, making them more similar to optical imaging...
Chemical exchange saturation transfer (CEST) imaging is a powerful magnetic resonance imaging (MRI) technique with unique contrast features. This t...
