David R. Brown Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK In 1982 Stanley Prusiner and colleagues puri?ed an abnormal protein from the brains of mice experimentally infected with a rare sheep dis- 1 ease called scrapie . This protein was called the prion protein. Earlier work had suggested that this diseases and others, loosely collected - gether as transmissible spongiform encephalopathies (TSEs), were not transmitted by conventional infectious agents. Prusiner suggested that 2 this new protein was the infectious agent in these diseases . Such a contentious...

This book will appeal to both chemists and biologists at the post graduate and research level.

Since the discovery of the pancreatic secretagogue secretin by W. M. BAYLISS and E. H. STARLING at the inception of the twentieth century, intense interest has focused on numerous, continually expanding classes of small peptides which appear to serve as regulatory molecules in the gastrointestinal tract, brain, and other organ systems. Initially, many of these substances were, like secretin, discovered in functional assays as "factors" or "activities" extractable in minute quantities from tissues or tissue fluids. By the middle of the century, advances in biochemical and immunological methods...

Richard Kepperman was on top of his game until blowing the whistle on his high powered Atlanta accounting firm. Black balled from the financial arena, on the verge of bankruptcy, he returns to his roots in coastal Georgia to be near his aging grandfather, Clayton. Frustrated and underemployed, he is an easy mark when approached by a stranger who offers to bet ten million dollars that he can capture Richard within a span of thirty days. In return, Richard will be required to risk all that he holds dear. Given a twenty four hour head start, Richard embarks on an odyssey that will forever change...

"I am Your Neighbor" is a story of community. It is a collection of stories from 21 people on Chicago's North Side who are clients of the Common Pantry, a non-profit organization that provides emergency groceries and other services to qualifying individuals and families. 100% of all proceeds from book sales will be donated to the Common Pantry to continue their mission of food distribution and expanded services during their Wednesday afternoon "Common Community."

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