Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads. ...
Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research ...
In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged: Microreactor chemistry; Nanotechnology and catalysis research; Microwave-assisted organic synthesis; New developments in solid supported synthesis.
This book covers lectures about the theory, use, scope and limitations of these new technologies in chemical synthesis. It provides a useful overview for scientists in the pharmaceutical industry as...
In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and dr...
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant...
Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life...
The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies.
Glycans (carbohydrate oligomers) are the so-called building blocks of carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research...
The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view a...
