This is a study of algebraic differential modules in several variables, and of some of their relations with analytic differential modules. Let us explain its source. The idea of computing the cohomology of a manifold, in particular its Betti numbers, by means of differential forms goes back to E. Cartan and G. De Rham. In the case of a smooth complex algebraic variety X, there are three variants: i) using the De Rham complex of algebraic differential forms on X, ii) using the De Rham complex of holomorphic differential forms on the analytic an manifold X underlying X, iii) using the De Rham...