"A valuable addition to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help will be impressive and of great benefit to humankind." --From the Foreword by E. J. Corey, Nobel Prize Laureate
An invaluable guide to name reactions and reagents for homologations
Name Reactions for Homologations, Part I of Wiley's Comprehensive Name Reactions series comprises a comprehensive treatise on name reactions for homologations. With contributions from world-recognized authorities in the field, this...
"A valuable addition to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help wi...
The up-to-DATE guide to name reactions in heterocyclic chemistry
Name Reactions in Heterocyclic Chemistry II presents a comprehensive treatise on name reactions in heterocyclic chemistry, one of the most exciting--and important--fields within organic chemistry today.
The book not only covers fresh ground, but also provides extensive information on new and/or expanded reactions in:
Three- and four-membered heterocycles
Five-membered heterocycles (pyrroles and pyrrolidines, indoles, furans, thiophenes, and oxazoles)
...
The up-to-DATE guide to name reactions in heterocyclic chemistry
Name Reactions in Heterocyclic Chemistry II presents a comprehensive treati...
Sets forth the history, state of the science, and future directions of drug discovery
Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug...
Sets forth the history, state of the science, and future directions of drug discovery
Edited by Jie Jack Li and Nobel laureate E. J. ...
For the world's largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizer's Lipitor, GlaxoSmithKline's Advair, AstraZeneca's Seroquel, and Sanofi-Aventis and Bristol-Myers Squibb's Plavix all came off patent in the crucial U.S. market. This so-called "patent cliff" meant hundreds of billions of dollars in lost revenue and has pharmaceutical developers scrambling to create new drugs and litigating to extend current patent protections. Having spent most of his career in drug discovery in "big pharma," Dr. Li now delivers an insider's account of...
For the world's largest prescription drug manufacturers, the last few years have been a harrowing time. Recently, Pfizer's Lipitor, GlaxoSmithKline's ...
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic...
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natur...
Greener than conventional methods, C H activation methods have flourished during the last decade and become especially attractive to organic chemists. Edited by a practioner in this rapidly developing field, C H Bond Activation in Organic Synthesis provides an overview of this exciting playground of chemistry. The book summarizes the state of the art in C H activation for functionalization, enabling you to carry out reactions in the most environmentally friendly fashion with the least contamination of by-products.
The most popular C H activation reactions are catalyzed by...
Greener than conventional methods, C H activation methods have flourished during the last decade and become especially attractive to organic chemis...
This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors' 3 successful drug synthesis books, this provides expert analysis of the pros and cons of different synthetic routes and demystifies the process of modern drug discovery for practitioners and researchers.
Summarizes for each drug: respective disease area, important properties and SAR (structure-activity relationship), and chemical synthesis routes / options
Includes case studies in each chapter
Illustrates...
This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors'...
Written by experts in organic chemistry, this book covers a range of natural products, from steroids to alkaloids. Coverage details the biological and pharmacological properties of the natural product and outlines current total synthesis procedures.
Written by experts in organic chemistry, this book covers a range of natural products, from steroids to alkaloids. Coverage details the biological and...
Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack...
Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality o...
Carbocation chemistry is not only fundamental to the advancement of organic chemistry, it also has found widespread applications in organic synthesis. It is not an exaggeration to say that carbocation chemistry is part of the foundation of organic chemistry. Carbocation Chemistry: Applications in Organic Synthesis provides a panoramic view of carbocation chemistry with an emphasis on synthetic applications.
This book is an invaluable tool for organic, medicinal and analytical chemists, including those working in biochemistry as well as the petroleum, plastics and pharmaceutical...
Carbocation chemistry is not only fundamental to the advancement of organic chemistry, it also has found widespread applications in organic synthesis....