Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry

ISBN-13: 9783642440922 / Angielski / Miękka / 2015 / 279 str.

Jie Jack Li; E. J. Corey

Opis

Written by experts in organic chemistry, this book covers a range of natural products, from steroids to alkaloids. Coverage details the biological and pharmacological properties of the natural product and outlines current total synthesis procedures.

Spis treści

Nominine.- Nakiterpiosin: A Novel C-nor-D-homosteroid.- The Kinamycins.- A Short Synthesis of Strychinine from Pyridine.- Bryostatin 7.- Serratezomine A.- Hypocrellin/Cercosporin.- Total Synthesis of Phomactin A.- (+)-11,11'-Dideoxyverticillin A.- Retigeranic Acid.- Companadine A.

O autorze

E. J. Corey has been a Professor at Harvard University since 1959. He was educated at The Massachusetts Institute of Technology (1945-50) and served as a faculty member at the University of Illinois from1951 to 1959. He is the 1990 Nobel Laureate in Chemistry, and the recipient of over seventy international awards and honorary degrees, including the U.S. National Medal of Science, the Japan Prize in Science, and the Priestley Medal of the American Chemical Society. He is amember of the U.S. National Academy of Sciences and the U.S. National Institute of Medicine.

Blurb

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.