This book covers generation, optimization, characterization, production and applications of antibodies, offering theoretical background and describing methods for expression of antibody in microbial and animal cell cultures and transgenic animals and plants.
This book covers generation, optimization, characterization, production and applications of antibodies, offering theoretical background and describing...
Developments in tissue engineering for human medicine are increasing rapidly. Advances in stem cell biology, biomaterials science and scaffold design underpin this emerging science. An equally important facet of this field is the rational design and operation of bioreactors to control the nascent tissue growth. For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed.
Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the...
Developments in tissue engineering for human medicine are increasing rapidly. Advances in stem cell biology, biomaterials science and scaffold desi...
A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metabolomics and fluxomics approaches, examination of the utility of modulation...
A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall...
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical...
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate condi...
Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in...
Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase signi...
The aim of this volume is to provide an in-depth overview of the state-of-the-art research on apoptosis with contributions from key groups working in the field. This type of programme cell death has received wide and rapid attention and now is considered as one of the hottest areas of science. The volume covers various aspects of the apoptotic death process from the morphological and biochemical features, mechanisms and genetic regulation to its role in pathological process and potential implications for biomedical research and biopharmaceutical production.
The aim of this volume is to provide an in-depth overview of the state-of-the-art research on apoptosis with contributions from key groups working in ...
Animal cells are the preferred cell factories for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve...
Animal cells are the preferred cell factories for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnos...
A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a recommended volume for all biotechnology libraries.
A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential read...
This book offers methodologies for virus production, transferring protocols, and evaluating the efficacy of gene products. Covers the basic principles of popular and less common viral vector systems, using the successful Methods in Molecular Biology(TM) format.
This book offers methodologies for virus production, transferring protocols, and evaluating the efficacy of gene products. Covers the basic principles...
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical...
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate condi...
