Bioreactors for Tissue Engineering: Principles, Design and Operation

ISBN-13: 9789048169498 / Angielski / Miękka / 2011 / 376 str.

Julian Chaudhuri; Mohamed Al-Rubeai

Opis

Developments in tissue engineering for human medicine are increasing rapidly. Advances in stem cell biology, biomaterials science and scaffold design underpin this emerging science. An equally important facet of this field is the rational design and operation of bioreactors to control the nascent tissue growth. For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.

Spis treści

1 Bioractor systems for tissue engineering: A four dimensional challenge by M. Ellis, M. Jarman-Smith, J.B. Chaudhuri
2 Microreactor optimization for functional tissue engineering by W.W. Minuth, R. Strehl, K. Schumacher
3 Taylor-vortex bioreactors for enhanced mass transport by S.J. Curran, R.A. Black
4 Packed bed bioreactors by J.N. Warnock, K. Bratch, M. Al-Rubeai
5 Design and operation of a radial flow bioreactor for reconstruction of cultured tissues by M. Kino-Oka, M. Taya
6 Cartilage growth in magnetic resonance microscopy-compatible hollow fiber bioreactors by J.B. Greco, R.G. Spencer
7 Mechanical conditioning of cell-seeded constructs for soft tissue repair – Are optimisation strategies possible? by D.L. Bader, D.A. Lee
8 Mechanical bioreactors for bone tissue engineering by S.H. Cartmell, A.J. El Haj
9 A dynamic straining bioreactor for collagen-based tissue engineering by Y. Shi, I. Vesely
10 Bioreactors for ligament engineering by B.J. Ainsworth, J.B. Chaudhuri
11 Biomechanical considerations for tissue engineered heart valve bioreactors by M.S. Sacks, G.C. Engelmayr Jr., D.K. Hildebrand, J.E. Mayer Jr.
12 Design of vascular graft bioreactors by P.S. McFetridge, J.B. Chaudhuri
13 Perfusion bioreactors for cardiovascular tissue engineering by V. Kasyanov, J.J. Sistino, T.C. Trusk, R.R. Markwald, V. Mironov
14 Haematopoietic culture systems by L. Safinia, N. Panoskaltsis, A. Mantalaris
15 Monitoring the performance of tissue engineering bioreactors using magnetic resonance imaging and spectroscopy by A.A. Neves, K.M. Brindle
16 Cryopreservation of hepatocytes for bioartificial liver devices by M.H. Grant, D. Stevenson