Many investigations into the structure and function of cells and tissu es require the isolation of a particular membrane or subcellular compo nent (organelle). This book covers all the necessary aspects, from the homogenization of cells via a variety of separation techniques, to th e isolation and characterization of peroxisomes and other organelles. Basic separation techniques needed in all cell biology laboratories ar e given and presented in the context of a number of related topics suc h as the labelling of ligands, the kinetics of their internalization a nd analysis of data, and the...

We see the stories in the newspaper nearly every day: a drug hailed as a breakthrough treatment turns out to cause harmful side effects; controls implemented to reduce air pollution are shown to generate hazardous solid waste; bans on dangerous chemicals result in the introduction of even more risky substitutes. Could our efforts to protect our health and the environment actually be making things worse? In Risk versus Risk, John D. Graham, Jonathan Baert Wiener, and their colleagues at the Harvard Center for Risk Analysis marshal an impressive set of case studies which demonstrate that...