All aspects of oxygen transport and tissue oxygenation that are relevant in clinical medicine are covered in this monograph. Experts from basic science as well as clinical research provide information that improves understanding of how to treat O2-transport disturbances in daily practice. Special interest is focussed on the question of supply dependency of O2-uptake and its role in multi-organ failure in the critically ill. Other topics are the clinical monitoring of O2-transport and O2-utilisation, oxygen toxicity, and the role of O2-radicals and the reperfusion syndrome in organ...

Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. In recent years, new therapeutic approaches have been developed on the basis of a better understanding of this complex condition. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine. It provides an up-to-date overview of the etiology, pathophysiology, prevention, and therapy of sepsis and its complications.

Sepsis und septischer Schock gehen auch heute noch trotz aller Fortschritte der Intensivmedizin mit einer ausserst hohen Mortalitat einher. Auf der Basis eines verbesserten Verstandnisses der Pathophysiologie dieses komplexen Krankheitsbildes haben sich in den letzten Jahren neue therapeutische Ansatze entwickelt. Dieses Buch enthalt die Beitrage namhafter Grundlagenforscher und Kliniker aus Hygiene, Mikrobiologie, Infektologie, Physiologie, Chirurgie, innerer Medizin, Anasthesiologie und Intensivmedizin und gibt einen umfassenden Uberblick uber den derzeitigen Wissensstand zur Atiologie,...