The role of the metals copper, zinc, magnesium, lead, manganese, mercury, lithium and aluminium in neuropsychiatric disease are well known and has been discussed on several occasions. Yet little attention has been paid to iron, the most abundant transitional metal in the body and the earth's crust. Iron plays a major role as a cofactor of numerous metabolic enzymes, it is important for DNA and protein synthesis, and has a crucial role in the oxygen carrying capacity of haemoglobin. Some of the most devastating diseases of systemic organs are associated with abnormal iron metabolism. Yet only...

Volume 5 of the series "Advances in Research on Neurodegeneration" is concerned with themes which are currently the focus of intensive research, and in which advances in our understanding of the pathological mechanisms un- derlying neurodegenerative diseases are expected in the near future. The first section contains five reviews devoted to the various neuroimaging technolo- gies. The discussion is concerned with the question of whether neuroimaging techniques make it possible to follow the process of degeneration as it occurs, and which methods offer the required sensitivity and...

This volume contains the proceedings of the symposium Pathochemical Markers in Major Psychoses, held in Vienna in July 1983. The development of biological markers in psychiatric diseases, par ticularly in the field of neurochemistry, has made substantial progress during recent years although the multiple mechanisms of mental illness are still not fully understood. The greatest contribution has come through the development of new therapeutic agents that not only pro vide invaluable help for psychiatric patients but also serve as chemical tools for the investigation of the biological mechanisms...

The scientific work of Walther Birkmayer is grounded on his ability to turn what was often a mass of clinical details into the basis for a hypothesis for a new therapeutic approach toward solving the problems of a patient's illness. Birkmayer first became known when, during the Second World War, he built up a clinic for brain injuries in Vienna, in which over 3000 patients were treated. The study of changes in the autonomic functions of the nervous system in these patients as well as the problems of rehabilitation were published in a monograph, "Hirn- verletzungen". Consequently, this was his...

Neuro-Psychopharmaka zahlen zu den meistverordneten Medikamenten, dennoch fallt vielen Arzten der Uberblick schwer. Das kompakte Taschenbuch enthalt die praxis- und verordnungsrelevanten Fakten als tabellarische Kurzinformationen zu knapp 200 Einzelsubstanzen. Die im deutschen Sprachraum erhaltlichen Neuro-Psychopharmaka sind alphabetisch nach ihren Internationalen Freinamen (INN) aufgefuhrt. Der Aufbau gliedert sich in 6 Spalten: - Freinamen (INN) alphabetisch, dazu Handelsnamen (D, A, CH) - Substanzcharakteristik (Pharmakologie, Indikationen, Wirkprofil) - Dosierung (einschliesslich...

Professor Walther Birkmayer, einer der Mitentdecker der neurochemischen Ursachen und der Substitutionstherapie des fehlenden Transmitters bei der Parkinson-Krankheit, und Professor Peter Riederer haben in dem vorliegenden Werk erfolgreich versucht, das derzeitige Wissen um die Bioche mie, die synaptische Ubertragung zwischen Neuronen, zu deren Erforschung beide Autoren wesentlich beigetragen haben, zusammenfassend darzustellen und mit den Ergeb nissen der Verhaltensforschung in Beziehung zu setzen. Unter menschlicher Verhaltenskunde oder Human-Etho logie verstehen wir jenes Wissen um...

Zu den haufigsten Alterserkrankungen zahlen heute die Parkinson sche Erkrankung sowie Demenzen. Eine Reihe neuer Erkenntnisse der Grundlagenforschung sowie die Entwicklung neuer Neuro-Psychopharmaka fur die genannten Indikationen machten eine Neubearbeitung des Bandes erforderlich. In den vergangenen zwei Jahren wurden unter den Parkinson-Mitteln neue Dopamin-Agonisten, COMT-Hemmer sowie NMDA-Antagonisten zugelassen. Zur Behandlung der Alzheimer-Demenz wurden Antidementiva (Cholinesterosehemmer) entwickelt, weitere medikamentose Therapieeinsatze befinden sich im Stadium der klinischen Prufung...

Presents findings of basic and clinical research on extrapyramidal disorders and allied conditions. Various insights on the nature of extrapyramidal dysfunction and its therapy in the fields of neurology, psychiatry and neuroscience are also presented.

Experts in the fields of neurology, neuroscience, neurobiology and psychiatry review and present novel findings of basic and clinical research on extrapyramidal disorders and allied conditions. New insights on the nature of extrapyramidal dysfunction and its therapy in the fields of neurology, psychiatry and neuroscience are presented.