This comprehensive introduction to both underlying principles and experimental procedures, covers the structure and NMR of biopolymers, including 2D NMR and Nuclear Overhauser effects; resonance assignments and structure determination in proteins; and resonance assignments and structure determination in nucleic acids. Also provided is an account of NMR studies for chemists, biochemists, biophysicists and molecular biologists concerned with structure and function of proteins and nucleic acids. The book aims to enable specialists and non-specialists to evaluate the potentialities and...

The volume presents a survey of the research by Kurt W thrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological...

This survey of research by Kurt Wuethrich discusses the development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution; and reprints some of Wuethrich's papers on the use of NMR spectroscopy in structural biology.