The design of structural steel members has developed over the past century from a simple approach involving a few basic properties of steel and elementary mathematics to a more sophisticated treatment demanding a thorough knowledge of structural and material behavior. Steel Structures: Design and Behavior, 5/e strives to present in a logical manner the theoretical background needed for developing and explaining design requirements. Beginning with coverage of background material, including references to pertinent research, the development of specific formulas used in the AISC...

The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general

The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general

Although thousands of articles and hundreds of books on aging have been published, only a small percentage of this material has dealt with anatomy, particularly at the fine structural level. It was with this in mind that Aging and Cell Structure was conceived. Volume 1 of Aging and Cell Structure was published in 1981 and represented a current compilation of information, concentrating at the electron microscopic level, on morphological changes which occur in cells and tissues as they age. The present volume completes the two-volume set. While Volume 1 highlighted structural changes occurring...

Approaching any task on aging brings a flood of images that are a personal repetition of what has been one of the greatest and most persistent concerns of mankind. Even restricting time to the past decade or so and approaching only the biomedical sciences, one still encounters a flood of information in this relatively young research area. The ories and ideas abound as though each researcher provides one of his own. This might well be expected; aging is an exceedingly complicated series of crossroads involving trails and even superhighways. Each specialist has a peephole (society, body, organ,...