This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencinganalyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein...
This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve ...
"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational...
"Applied Computational Genomics" focuses on an in-depth review of statistical development and application in the area of human genomics including cand...
"Bioinformatics of Human Proteomics" discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis,...
"Bioinformatics of Human Proteomics" discusses the development of methods, techniques and applications in the field of protein bioinformatics, an impo...
The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics...
The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on int...
Thebookis intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map came out in 2002, and the Proteome Sequence Map is under currently being created by a global consortia initiative. Proteome and genome building blocks already form the basis of scientific research areas as well as large parts of the pharmaceutical and biomedical industry. The book initiative will provide the background to and our...
Thebookis intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomi...
The volume will specially focus on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding molecular mechanisms of systems immunology. The present volume will provide readers revealing insights into and share personal experience on the potential application, significance, workflow, comparison, perspective in future, and challenges of single cell sequencing for discovery and development of disease-specific biomarkers, to understand biological function, activation, or dysfunction of single cells or lymphocytes, to explore...
The volume will specially focus on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understa...
Bioinformatics of Human Proteomics discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis,...
Bioinformatics of Human Proteomics discusses the development of methods, techniques and applications in the field of protein bioinformatics, an import...
This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key...
This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigeno...
The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring...
The book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the p...
This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr....
This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medi...
