This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on...
This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many esse...
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their...
All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins ar...
Cells of all living organisms have the ability to respond to altered nutritional conditions. They have developed mechanisms to sense nutrient availability and to produce appropriate responses, which involve changes in gene expression and the production or degradation of certain enzymes and other proteins. In recent years, the understanding of nutrient-induced signal transduction has greatly advanced and the emerging picture is that nutrient signalling mechanisms evolved early in evolution. This book provides a detailed presentation and comparison of the key nutritional regulatory...
Cells of all living organisms have the ability to respond to altered nutritional conditions. They have developed mechanisms to sense nutrient avail...
The series of review articles presented in this book summarizes the recent state of the art in lipid research in a comprehensive way. The authors provide a general overview of this field and draw the reader's attention to the most recent investigation. Biochemical, cell biological and biophysical aspects of the four major groups of lipids in eukaryotic cells, namely glycerophospholipids, sterols, sphingolipids and storage lipids, are reported and discussed. The experimental systems addressed are mammalian, plant and yeast cells as the most prominent and currently best studied systems in...
The series of review articles presented in this book summarizes the recent state of the art in lipid research in a comprehensive way. The authors p...
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes.
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in ou...
Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.
This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and...
Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whol...
This book defines the field of systems biology, one of the newest and fastest developing fields in science today. It discusses the most effective experimental and computational strategies and highlights new and emerging applications. Cell biologists and other readers will discover many benefits for industry, such as the new network-based drug-target design validation. The authors also thoroughly explore testing.
This book defines the field of systems biology, one of the newest and fastest developing fields in science today. It discusses the most effective e...
In this volume, studies on organisms, ranging from aquatic cyanobacteria that produce akinetes to hibernating mammals, are presented. They reveal common and divergent physiological and molecular pathways for surviving in a dormant form or for tolerating harsh environments.
In this volume, studies on organisms, ranging from aquatic cyanobacteria that produce akinetes to hibernating mammals, are presented. They reveal comm...
In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-faceted genetic repertoire of several yeasts relevant to modern biotechnology, and describes their utilization in research and application in the light of their genetic make-up and physiological characteristics. Moreover, the book presents a thorough overview of a wide array of methodologies from classical genetics to modern genomics technologies that have been and are being used in functional analysis of yeasts.
In recent years, new yeast species have proven their value and novel biotechnological applications have emerged. This book compiles the multi-facet...
Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.
This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and...
Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whol...
