Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to...

to the expression of oncogenes, which are pivotal in cancer genetics. Accurate delineation and prognosis of a cancer may depend upon careful cytogenetic analysis. Cytogenetics is still of great importance when monitoring changes in somatic cell hybrids. The role of chromosome genetics within modern biology is continually changing and evolving, and thus a knowledge of cytogenetics is of ever-increasing value. Chromatin structure 1 and replication Summary It is now a well-known fact that DNA is the hereditary material and that the vast majority of the DNA of an organism is housed in organelles...

In this volume, studies on organisms, ranging from aquatic cyanobacteria that produce akinetes to hibernating mammals, are presented. They reveal common and divergent physiological and molecular pathways for surviving in a dormant form or for tolerating harsh environments.

Many organisms have evolved the ability to enter into and revive from a dormant state. They can survive for long periods in this state (often even months to years), yet can become responsive again within minutes or hours. This is often, but not necessarily, associated with desiccation. Preserving one's body and reviving it in future generations is a dream of mankind. To date, however, we have failed to learn how cells, tissues or entire organisms can be made dormant or be effectively revived at ambient temperatures. In this book studies on organisms, ranging from aquatic cyanobacteria that...

Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to...