Gastroesophageal Reflux and the Lung provides a comprehensive review of current knowledge concerning normal deglutition and foregut digestive processes and examines how abnormalities of swallowing or excessive/abnormal GER can lead to respiratory tract dysfunction and lung disease. In-depth Chapters deliver a concise review of the prevalence of GER in patients with lung disease and synthesize the current evidence regarding its diagnosis and management. Each chapter includes key points and a summary. In addition to outlining the current state of knowledge, each chapter...
Gastroesophageal Reflux and the Lung provides a comprehensive review of current knowledge concerning normal deglutition and foregut d...
Alcohol Use Disorders and the Lung: A Clinical andPathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings.Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these samepathophysiological effects of alcohol abuse significantly increase the risk of a wide range ofserious lung infections.Many clinicians...
Alcohol Use Disorders and the Lung: A Clinical andPathophysiological Approach is an excellent resource for clinicians who care for individuals ...
Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is a valuable resource for clinicians of varied disciplines concerning the care of the sarcoidosis patient. Sarcoidosis is a multi-system disorder and represents a major challenge to physicians. Although any organ may be involved with sarcoidosis, the lung is the most common organ affected. Chapters are written by distinguished authors who have extensive experience in caring for these patients. Detailed figures and tables are provided to guide the practicing clinician through all aspects of the condition, from clinical...
Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is a valuable resource for clinicians of varied disciplines concerning the care of ...
The origin of modern intensive care units (ICUs) has frequently been attributed to the widespread provision of mechanical ventilation within dedicated hospital areas during the 1952 Copenhagen polio epidemic. However, modern ICUs have developed to treat or monitor patients who have any severe, life-threatening disease or injury. These patients receive specialized care and vital organ assistance such as mechanical ventilation, cardiovascular support, or hemodialysis. ICU patients now typically occupy approximately 10% of inpatient acute care beds, yet the structure and organization of these...
The origin of modern intensive care units (ICUs) has frequently been attributed to the widespread provision of mechanical ventilation within dedicated...
Mitochondria, often referred to as the "powerhouses" of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases...
Mitochondria, often referred to as the "powerhouses" of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and ma...
Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic administration and sedation and analgesia. However, despite improved clinical care, many critically ill patients continue to experience complications of critical illness - some complications are iatrogenic and preventable, while others are simply a component of the natural history of critical illness. These complications lead...
Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive ...
People age 65 and older are the fastest growing segment of the U.S. population. In the 2010 census 16% of the population, 50 million people, were age 65 and older. That number is projected to increase to 66 million by the year 2050. Life expectancy has also increased, with recent CDC reports indicating life expectancy at 77.9 years. Age-adjusted death rates have decreased significantly with the largest changes occurring in older patients. Despite these trends, the 10 leading causes of death include several pulmonary etiologies including lung cancer, chronic respiratory diseases, influenza...
People age 65 and older are the fastest growing segment of the U.S. population. In the 2010 census 16% of the population, 50 million people, were a...
Sleep disorders represent a major portion of the chief complaints seen by pulmonologists and other physicians. Sleep apnea and hypopnea syndrome for example, are common disorders with significant adverse health consequences. Sleep apnea is associated with increased cardiovascular mortality, impaired quality of life and increased motor vehicle accidents. In addition, sleep apnea often co-exists with other chronic conditions including obesity, the metabolic syndrome, and tobacco use disorder. Patients with sleep-related conditions often present with non-specific complaints that require a...
Sleep disorders represent a major portion of the chief complaints seen by pulmonologists and other physicians. Sleep apnea and hypopnea syndrome fo...
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. By 2020, COPD is expected to be the fifth leading cause of disability and the third leading cause of death. COPD is associated with significant co-morbid illnesses including cardiovascular disease, pulmonary vascular disease, osteoporosis, depression and thoracic malignancies. In addition, COPD patients often have systemic manifestations of their disease, including peripheral muscle dysfunction, decreased activity levels and nutritional abnormalities, all of which contribute to poor...
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. By 2020, COPD is expected to be the fifth leadi...
