Divided into six chapters, this guide covers basic concepts of HPLC; instrumentation; stationary phase materials; eluents; column efficiency; and the influence of physical chemistry on separations.

Thin-Layer Chromatography (TLC) is a modern, reliable tool that complements other chromatographic techniques. This book provides a practical guide to the basic principles, procedures and pitfalls on the practical application of TLC. Thin Layer Chromatography: A Modern Practical Approach offers a sequence of chapters following the steps of the technique as the chromatographer would follow them. The chapters provide a choice of sorbent best suited to the separation intended, followed by pre-treatment required for the sample, applying the sample to the sorbent layer, development procedure,...

This title introduces the basics of computer validation. It is ideal for the chromatographer and will be welcomed by consultants or those in regulatory agencies.

An introduction to packed column supercritical fluid chromatography (SFC), which familiarizes users with the more subtle aspects of this technique, and attempts to clear up some of the confusion surrounding the analytical use of supercritical fluids.

Fully referenced, Hyphenated Techniques in Speciation Analysis is an invaluable introduction to elemental speciation analysis.

This unique book covers all the practical aspects of setting up an HPLC system for high temperature operation.

This is a detailed and comprehensive account of the theory and practice of high performance chelation ion chromatography (HPCIC) for the trace determination of metals. It shows how HPCIC can rival atomic spectroscope techniques such as ICP-MS.

Metabolomics is an emerging field and this is the first book to present chromatographic techniques in metabolomics in a fundamental way. Sample preparation and quality control are crucial aspects which are described in detail. Uniquely, guidelines for the selection of appropriate methodology are also provided. The book covers the chromatographic techniques, such as liquid chromatography, gas chromatography, comprehensive two-dimensional gas chromatography and electrochromatographic techniques utilised in metabolomics.

An examination of supercritical fluid chromatography (SFC) with reference to its theory and more practical applications. Topics covered include the roles of packed and capillary columns and the coupling of SFC to mass spectrometry.

Guiding chromatographers working in regulated industries and helping to validate their chromatography data systems, this book will be a detailed look at the requirements to ensure a system is fit for purpose throughout the life cycle.