Volume 39 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the con- nection with the previous volumes. The articles in this volume deal with polyamines as tumor markers; the histamine (H3)-receptor and its role as a general regulatory system; with cytokines as immunosti- mulants and immunosuppressants as well as potential anticancer agents; with fibrinolysis and clinical use of thrombolytic agents; and with catechol O-methyltransferase and its inhibitors, which are of potential interest in the treatment of Parkinson's...
Volume 39 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the con- nection with t...
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors...
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for thei...
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors...
The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for thei...