Synthetic biology involves the rational design and construction of biological components and systemsfrom genetic elements and metabolic pathways to entirely new organisms. Progress in this field has been rapid, and it promises to significantly expand our capabilities in biotechnology, medicine, and agriculture. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the tools and techniques employed by synthetic biologists, how these may be used to develop new drugs, diagnostic approaches, food sources, and clean...
Synthetic biology involves the rational design and construction of biological components and systemsfrom genetic elements and metabolic pathways to en...
The adaptive immune system ensures that our bodies remember pathogens so that we can rapidly mount an immune response if they are encountered again, without succumbing to infection. This volume examines the basis of this immune memory and the roles of the T and B cells involved. Topics covered in this essential volume include: - Do memory CD4 T cells keep their cell type programming: Plasticity versus fate commitment? - Is it possible to develop a "universal" influenza vaccine? - What is the value of animal models in predicting vaccine efficacy in humans? - Is a human CD8 T...
The adaptive immune system ensures that our bodies remember pathogens so that we can rapidly mount an immune response if they are encountered again, w...
Cytokines are small proteins released by cells that regulate the behavior of other cells. They include interferons, interleukins, and tumor necrosis factor and are important regulators of the immune system. This book examines the spectrum of cytokines that are produced and their roles in normal physiology and disease. Topics covered in this essential volume include: - Cytokines and Long Noncoding RNAs - Negative Regulation of Cytokine Signaling in Immunity - Cytokines and metabolism - Cytokines and viral infection
Cytokines are small proteins released by cells that regulate the behavior of other cells. They include interferons, interleukins, and tumor necrosis f...
Prostate cancer is the second most common type of cancer and affects millions of individuals worldwide. This volume reviews our understanding of the disease, its progression, and new therapeutic approaches. Topics include: -Anatomy and Histology of the Human and Murine Prostate -Prostate Cancer Genetics -Prostate Cancer Disparities by Race and Ethnicity: From Nucleotide to Neighborhood -Stem Cells and Cancer Stem Cells -Epigenetics -New Opportunities for Targeting the Androgen Receptor in Prostate Cancer -Chemoprevention in...
Prostate cancer is the second most common type of cancer and affects millions of individuals worldwide. This volume reviews our understanding of the d...
Complexes that link neighboring cells play a critical role maintaining tissue integrity and allowing cells to communicate and remodel. This volume discusses structure and function of cell junctions and the roles they play in development and cancer.
Complexes that link neighboring cells play a critical role maintaining tissue integrity and allowing cells to communicate and remodel. This volume dis...
