Atherothrombosis refers to the coupling of atherosclerosis and thrombosis, and it is the leading cause of the majority of preventable deaths in the modern world. The medical, economic, social, and societal consequences or atherothrombosis are enormous, which make it a dynamic area for development of new pharmacologic agents. Atherothrombosis in Clinical Practice focuses upon the many clinical manifestations of atherothrombosis and therapies that presently exist, with a focus on evolving therapeutic approaches. First, atherothrombosis is defined and the epidemiology is explored. Then,...

Clinical practice consensus guidelines for management of heart failure are available from the American Heart Association/American College of Cardiology, Heart Failure Society of America, Canadian Cardiovascular Society, and European Society of Cardiology. The guidelines from these organizations, based on evidence from clinical trials and expert agreement, are largely concordant and provide useful information for practitioners. Yet, the organization of the guidelines may confound efforts by a practitioner to determine which specific intervention, or combination of interventions, are most...