The NATO Advanced Study Institute on "Cerebral Blood Flow: Mathematical Models, Instrumentation, and Imaging Techniques" was held in L'Aquila, Italy, June 2-13, 1986. Contributions to this program were received from the University of L'Aquila, Consiglio Nazionale delle Ricerche, Siemens Elettra S.p.A., and Bracco S.p.A. Recent studies of the cerebral blood circulation have lagged behind analysis of other parameters such as glucose utilization, transmitter distribution, and precursors. This Advanced Study Institute tried to fill this gap by analyzing in detail different physical techniques...

No more than a fish loves water. - Is not this a strange fellow, my lord, that so confidently seems to undertake this business, which he knows is not to be done; damns himself to do, and dares better be damn'd than to dolt? All's Well That Ends Well Act III, Sc. 6 This volume is the direct result of a NATO-Advanced Study Institute of the same title. held at Bishop's University, Lennoxville, Quebec, Canada, August 1974, under the joint sponsor- ship of the NATO-Scientific Advisory Committee, National Research Council of Canada and the Universite de Montreal. It is not, however, strictly...

Vaccination, chiefly responsible for the eradication of smallpox and the control of poliomyelitis and German measles in man and of foot-and- mouth, Marek's and Newcastle disease in domestic animals, remains the best answer to infectious diseases. Early vaccines were live wild type organ- isms but these have been largely replaced by attenuated or killed organisms or by purified components (subunits) thereof. More recently, developments in recombinant DNA techniques, the advent of monoclonal antibodies and progress in our understanding of the immunological structure of proteins, have laid the...

The present book is based on the papers presented during an inter- disciplinary meeting which was held in Rome October 27-30, 1986, at the Istituto Superiore di Sanita under the sponsorship of NATO, and with a financial contribution of the Cassa di Risparmio di Roma. The meeting was of great interest because, for the first time, a group of highly qualified scientists specializing in different fields were gathered together to discuss the problem of demyelinating diseases. In thi. context molecular biologists, immunologists, virologists, and lipid chemists could discuss with clinicians for four...

The principal purpose of a NATO (North Atlantic Treaty Organization) Advanced Research Workshop, a part of the NATO Advanced Study Institutes Programme, is to: (a) exchange thoughts at the frontiers of knowledge or at the frontiers of two (or more) fields or sectors; (b) review and assess the state of the art; (c) formulate recommendations for future research directions; (d) formulate plans for large international scientific experiments. The aim of the ARW on "Microvascular, rheological, metabolic and heat-transfer aspects of the heart: relation to ischaemia and thrombosis," convened in...

A NATO Advanced Study Institute on "Oxygen Radicals in Biological Systems: Recent Progress and New Methods of Study" was held in Braga, Portugal between Sep- tember 1 and September 14, 1985, in order to consider the basic chemistry and biochem- istry of activated oxygen (both radical and non-radical species) and their effect in biolog- ical systems. This book summarizes the main lectures given at this meeting. While there is no attempt to cover all the major topics in the expanding subject of oxidative mechanisms in biology, an effort has been made to provide overviews on some key aspects of...

This proceedings volume represents the culmination of nearly three years of planning, organizing and carrying out of a NATO Ad- vanced Study Institute on Biomass Utilization. The effort was initi- ated by Dr. Harry Sobel, then Editor of Biosources Digest, and a steering committee representing the many disciplines that this field brings together. . When the fiscal and logistical details of the original plan could not be worked out, the idea was temporarily suspended. In the spring of 1982, the Renewable Materials Institute of the State University of New York at the College of Environmental...

The pineal gland has been a subject of interest and speculation for more than 2000 years. Greek anatomists were impressed by the ob- servation that the pineal gland is an unpaired structure and they believed that it regulated the flow of thoughts. The philosopher Descartes proposed an important role for this organ in brain function. At the beginning of the 20th century experiments by several investi- gators indicated that the pineal influenced sexual function and skin pigmentation and was also responsive to light signals. With the iso- lation of melatonin from bovine pineal glands by Lerner...

One of the major advances in the understanding of the mechanism of action of hormones, neurotransmitters and drugs had arisen from the hypothesis that the physiological or pharmacological responses are trig- gered by their interaction with specific cell compo- nents, termed receptors. However, the presence of receptors has been inferred from indirect data, and only recently has it been possible to study the kinetics of the interaction between drug and receptors directly, through the so called "binding technique. " This NATO-ASI on "Principles and Methods in Receptor Binding" was devoted...