Damage to DNA by both exogenous and endogenous sources is increasingly regarded as highly important in the initiation and progression of cancer and in the occurance of other pathological events. DNA damage caused by reactive oxygen-derived species, also called oxidative DNA damage, is most the frequent type encountered by aerobic cells. Mechanistic studies of carcinogenesis indicate an important role of this type of damage to DNA. There is also strong evidence to support the role of oxidative DNA damage in the aging process. DNA damage is opposed in vivo by repair systems. If not...

Comprises 51 papers from the June 1997 conference. The papers are divided into six subject areas: sodium transport and fluid clearance across the normal and injured lungs; role of the pulmonary surfactant in the pathogenesis and treatment of acute respiratory distress syndrome (ARDS); ventilatory st

Fluorescence is a very powerful tool for work at the frontier of cell biology, photobiology and bioinstrumentation. The stated aim of the workshop was to highlight the significance of fluorescence work for the understanding of cell and tissue physiology, physiopathology and pharmacology, particulary in terms of the analytical use of fluorescent probes in oncology. In the organization of the workshop a multidisciplinary approach was selected. The purpose of the Advanced Research Workshop (ARW) was to bring together researchers in the various disciplines of tissue optics, imaging,...

The proceedings of a symposium held under the auspices of the Federation of European Microbiological Societies, September 1993, in Granada, Spain, devoted to microbial identification. Such a topic could not be addressed without some reference to the enabling discipline of classification, but the pri

Contains the revised and edited versions of papers presented at an October 1991 workshop held in San Miniato, Italy. Forty-six contributions are grouped in sections on cell biology, lymphocyte homing, viruses, histology, genotyping, and immunomodulation and tumor progression. A sampling of specific

The proceedings of the Second International Workshop on HPV Immunology, held in Cambridge, England, July 1993, comprise papers on topics in HPV gene expression, humoral responses to HPV, cell mediated immunity to HPV, and animal models and therapeutic strategies. Among the specific topics: the antib

Lyme borreliosis is a worldwide infectious disease causing a multisystem illness with considerable morbidity, particularly in North America and Europe. The causative agent is the spirochete Borrelia burgdorferi, which is usually transmitted by the ixodid tick from animal reservoirs. This volume sum

The problem is that, with the continuing degradation of water and habitat quality, selective harvesting, genetic enhancement programs, and the introduction of hatchery fish into wild populations, the genetic makeup of fish is changing radically. In 27 papers from a workshop held in Moscow, Idaho, an

Proceedings of an American Chemical Society symposium on Biosynthesis and Metabolism of Secondary Metabolite Natural Products, held April 1991, in Atlanta, Georgia. Bridging the gap between the fields of mechanistic bio-organic chemistry and biotechnology, contributions are in four main areas: antib

Before you lies the proceedings oft he NATO Advanced Study Institute/Newton Institute Workshop "Confinement, duality and non perturbative aspects of QCD." The school covered the most important techniques to study Quantum Chromodynamics (QCD) andconfinement, fromlattice gauge theory, through Wilson's renormalisation group, to electromagnetic duality. The organisingcommittee existed of: Ian Drummond (DAMTP, Cambridge), Mikhail Shifman (Minneapolis), Peter West (King's, London), and Pierrevan Baal (Leiden), who acted as director oft he school. This summer school was the concluding activity ofa...