Discusses the problem of structural-functional organization of eukaryotic cell nuclei with special emphasis on the genome spatial organization and functioning. The opening chapters describe the nuclear matrix and the fate of its components in the course of mitosis. In the next eight chapters the organization of chromosomal DNA into large loops and
Discusses the problem of structural-functional organization of eukaryotic cell nuclei with special emphasis on the genome spatial organization and fun...
Under the name of programmed cell death (PCD) are included diverse molecular mechanism of cell suicide which play an essential role in the development of multicellular organisms. The best known PCD mechanism in multicellular organisms is called apoptosis. However, recent studies indicate that PCD is also present in protozoa and unicellular eukaryotes. The eleven chapters of this book give the reader a comprehensive update of the progress in the understanding of the mechanisms of PCD in protozoa. The chapters have been written by experts in this field of research and are arranged following...
Under the name of programmed cell death (PCD) are included diverse molecular mechanism of cell suicide which play an essential role in the developm...
In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one...
In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zi...
Excluding the biological polymers proteins, lipids and nucleic acids, modified tetrapyrroles are the biological molecules that have had the greatest impact on the evolution of life over the past 4 billion years. They are involved in a wide variety of fundamental processes that underpin central primary metabolism in all kingdoms of life, from photosynthesis to methanogenesis. Moreover, they bring colour into the world and it is for this reason that these compounds have been appropriately dubbed the pigments of life . To understand how and why these molecules have been so universally...
Excluding the biological polymers proteins, lipids and nucleic acids, modified tetrapyrroles are the biological molecules that have had the greates...
This book presents a collection of revised refereed papers selected from the presentations accepted for the Second International Workshop on Higher-Order Algebra, Logic, and Term Rewriting, HOA '95, held in Paderborn, Germany, in September 1995. The 14 research papers included, together with an invited paper by Jan Willem Klop, report state-of-the-art results; the relevant theoretical aspects are addressed, and in addition existing proof systems and term rewriting systems are discussed.
This book presents a collection of revised refereed papers selected from the presentations accepted for the Second International Workshop on Higher-Or...
'VEGF in Development' is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates.
'VEGF in Development' is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for deve...
The intra-cellular trafficking field has made a quantum leap in the last few decades. The three sections of this book cover the past, present and future of this rapidly developing field.
The intra-cellular trafficking field has made a quantum leap in the last few decades. The three sections of this book cover the past, present and futu...
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.
Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work...
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to resul...
Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the...
Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law d...
