Over the last few years, the methods for analyzing cancer-related genes on a molecular level have changed rapidly. This text examines the world of cancer gene profiling in light of these new advances, providing highly-developed microarray techniques alongside modern methods for arraying tissues and proteomics.
Over the last few years, the methods for analyzing cancer-related genes on a molecular level have changed rapidly. This text examines the world of can...
This editor believes the public finally understands that bioenergy should be a critical new 39 component of our world s future energy supply. While this new enlightenment might have 40 come from bioenergy s environmentally friendly attributes and its renewable and sustain- 41 able nature, the reality is that the primary driver has been both the high cost of energy, 42 led recently by petroleum products, and the unique climatic changes such as local weather 43 events and reports of melting of ancient glaciers. I believe that much of the public under- 44 stands the primary cause of these...
This editor believes the public finally understands that bioenergy should be a critical new 39 component of our world s future energy supply. While th...
This second edition details the newest and most innovative techniques in this rapidly expanding field. It provides methods and assays that can be adapted and used in most specialties of biomedical and biotechnological fields.
This second edition details the newest and most innovative techniques in this rapidly expanding field. It provides methods and assays that can be adap...
This is a fundamental yet comprehensive guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research. It examines the world of cancer gene profiling in light of new advances.
This is a fundamental yet comprehensive guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area ...
As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies. In Cardiovascular Genomics: Methods and Protocols, experts in the field provide methods for cardiovascular phenotyping of rodent models in the first section of the volume and for statistical and bioinformatic integration of phenotype data with genome-wide genotype and expression data in the second section. Understanding these diverse methods...
As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the ge...
Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological function. The establishment, analysis, prediction, and expansion of a comprehensive ligand target SAR (structure activity relationship) matrix has followed the elucidation of the human genome and presents a key scientific challenge for the twenty-first century. The anno- tion and knowledge-based exploration of the ligand target SAR matrix is then expected to impact science greatly. Progress alongside this challenge without a doubt will c-...
Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological...
Fundamental to the development and vital functions of organisms, the migration of motile cells due to the detection of shallow gradients of specific chemical signals in their environments, or chemotaxis, can be clearly seen as a major force in cell biology. In Chemotaxis: Methods and Protocols, expert researchers in the field provide state-of-the-art methods for investigating cell migration behaviors, studying molecular components involved in detecting extracellular signals and directing cell movement, visualizing spatiotemporal dynamics of the components in signaling networks of...
Fundamental to the development and vital functions of organisms, the migration of motile cells due to the detection of shallow gradients of specifi...
Over the past twenty years, the development of chromatin immunoprecipitation, or ChIP, assays has immensely enhanced the biological significance of the multifaceted DNA-binding proteins. In Chromatin Immunoprecipitation Assays: Methods and Protocols, researchers deeply involved in the development and improvement of the field provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects. The thorough chapters involve topics such as the characterization of ChIP antibodies, ChIP methods for small cell numbers, fast ChIP protocols, assays adapted to...
Over the past twenty years, the development of chromatin immunoprecipitation, or ChIP, assays has immensely enhanced the biological significance of...
Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of research at the molecular and cellular levels continues to show a great deal of promise. In DNA Topoisomerases: Methods and Protocols, experts in the field present a compendium of protocols that extends into the new areas of research that have been recently uncovered in order to elucidate the methodology needed to study topoisomerases in the molecular and cellular context. The volume...
Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly f...
This highly practical book describes in step-by-step detail the powerful methods developed and optimized to analyze and manipulate epidermal cell precursors and mature epidermal cells. These protocols will benefit both novices and experienced investigators.
This highly practical book describes in step-by-step detail the powerful methods developed and optimized to analyze and manipulate epidermal cell prec...
