This volume, based on the International Congress Creatine: From Basic Science to Clinical Application, held in Milan on June 4, 1999, outlines the physiological role of creatine in the human body as well as its possible role in different pathological conditions. Creatine is already used as a dietary supplement to augment muscle performance in healthy individuals and inpatients with immobilizing diseases, such as complex fractures. There is also an increasing interest in its administration in a growing number of clinical conditions. A specific deficit of endogenous synthesis of creatine which...

Reference to Abstract Objects in Discourse presents a novel framework and analysis of the ways we refer to abstract objects in natural language discourse. The book begins with a typology of abstract objects and related entities like eventualities. After an introduction to bottom up, compositional' discourse representation theory (DRT) and to previous work on abstract objects in DRT (notably work on the semantics of the attitudes), the book turns to a semantic analysis of eventuality and abstract object denoting nominals in English. The book then substantially revises and extends the...

This book reports the more policy-oriented results of the Biodiversity programme of the Royal Swedish Academy of Sciences Beijer Institute. The programme brought economists and ecologists together to consider where the problem in biodiversity loss really lies, what costs it has for society, and how it might best be addressed. The results are strikingly different from those reported in other works on the subject. Biodiversity loss matters for all ecosystems -- not just the megadiversity tropical forests. And it matters because it compromises the resilience and so the productivity of those...

Despite its universality in human female ageing, the menopause and its biology are not completely understood. New biologic mechanisms by which sex hormones may be detrimental or confer protection are continually being discovered.

The issue of interaction of risk factors in cardiovascular disease is discussed in this text which is a collection of the scientific contributions to the 4th International Symposium on Multiple Risk Factors and Cardiovascular Disease: Strategies of Prevention of Coronary Heart Disease, Cardiac Failure, and Stroke. The book addresses the role of simultaneous risk factors in patients. Because patients with two or more risk factors are at very high risk for developing cardiovascular diseases, special care should be taken in the choice of appropriate therapeutic intervention.

The complex relationships between alcohol use and human health represent an area of increasing interest to specialists interested in preventive cardiology. The inverse relationship between alcohol consumption and the incidence of cardiovascular diseases, especially myocardial infarction and ischemic stroke, has in fact gained sound scientific support in the last few years of the 20th century. This book, based in an international symposium on the topic held in Venice, October 30-31, 1999, analyzes in depth the epidemiological association between alcohol consumption and human diseases and...

The control of optical modes in microcavities or in photonic bandgap (PBG) materials is coming of age Although these ideas could have been developed some time ago, it is only recently that they have emerged, due to advances in both atomic physics and in fabrication techniques, be it on the high-quality dielectric mirrors required for high-finesse Fabry- Perot resonators or in semiconductor multilayer deposition methods. Initially the principles of quantum electro-dynamics (QED) were demonstrated in elegant atomic physics experiments. Now solid-state implementations are being investigated,...