Population genetics thrives on the constant interaction between theoretical and empirical knowledge. In the first instance, population genetics was developed using a one locus, two allele model for genetic variation. The simplicity of these models opened up population and evolutionary genetics to biologists without specialist training in mathematics. Population genetics of multi-allelic loci is more complex and requires a degree of mathematical insight, therefore its study is In this presentation, the author provides a unified theory which demonstrates that multi-locus theory need not be an...

Rapid developments in experimental techniques continue to push back the limits in the resolution, size, and complexity of the chemical and biological systems that can be investigated. This challenges the theoretical community to develop innovative methods for better interpreting experimental results. Normal Mode Analysis (NMA) is one such technique. Capable of providing unique insights into the structural and dynamical properties of complex systems, it is now finding a wide range of applications in chemical and biological problems.
From the fundamental physical ideas to cutting-edge...

Guiding readers from the elucidation and analysis of a genomic sequence to the prediction of a protein structure and the identification of the molecular function, Introduction to Bioinformatics describes the rationale and limitations of the bioinformatics methods and tools that can help solve biological problems. Requiring only a limited mathematical and statistical background, the book shows how to efficiently apply these approaches to biological data and evaluate the resulting information.

The author, an expert bioinformatics researcher, first addresses the ways of storing and...

Spatio-temporal pattern formation is a major area of research within the subject of mathematical biology. The topic involves the use of mathematical modelling to analyse how patterns in biology are created and develop. For example, the growth, over time, of the intricate and beautiful patterns on certain sea-shells or the striped markings on a tiger can be modelled and their development predicted in terms of nonlinear mathematical processes. The current volume captures the breadth of recent research into various aspects of spatio-temporal pattern and form, such as development biology,...