This revised edition continues to provide a beautifully written, accessible introduction to the physical and quantitative aspects of biological systems and processes involving macromolecules, subcellular structures, and whole cells. It includes two entirely new chapters covering experimental techniques, to complement coverage of mathematical and computational tools, as well as additions to its multimedia component of video clips and animations, as well as interactive diagrams and graphs.

This book introduces the concepts and practical tools necessary to understand the behavior of biological macromolecules at a quantitative level. It begins by describing biochemical phenomena using principles of classical and statistical thermodynamics. Unlike other books, this text goes beyond theory to explain in detail how the equations are applied to the analysis of experimental measurements. This emphasis on real-world applications is continued throughout and is a major feature of the book.

Praise for the First Edition

"essential reading for any physical scientist who is interested in performing biological research." ―Contemporary Physics

This fully updated and expanded text is the best starting point for any student or researcher in the physical sciences to gain firm grounding in the techniques employed in molecular biophysics and...