More than ten years have elapsed since the publication of a compre hensive review on the quassinoids, the bitter principles of the Simaroubaceae family (80). Interest in these terpenoids has increased enormously in recent years due in part to the finding of the American National Cancer Institute in the early 1970s that these compounds display marked antileukemic activity. Furthermore, a wide spectrum of other biological properties for the quassinoids has been discovered and studies on chemical modifications of inactive members to yield biologically active ones were undertaken. New structures...
More than ten years have elapsed since the publication of a compre hensive review on the quassinoids, the bitter principles of the Simaroubaceae famil...
The metabolic products of micro-organisms can be classified either as compounds of primary metabolic concern or else as secondary metabolites - substances which are apparently non-essential to the producing or- ganism. Fungi have a remarkable capacity to produce such secondary metabolites, e. g. mycotoxins with a diverse array of structural and pharmacological properties (1). The present resurgence of interest in all aspects of mycotoxin research (2, 3) can be related to the impact of the hepatotoxins (aflatoxin, sporidesmin, and phomopsin), nephrotoxins (ochratoxin and citrinin), and dermal...
The metabolic products of micro-organisms can be classified either as compounds of primary metabolic concern or else as secondary metabolites - substa...
Isocoumarins have been isolated from a wide variety of microbial, plant and insect sources and have been shown to possess an impressive array of biological activities. Since the review by BARRY in 1963 (24), the number of known naturally occurring isocoumarins has increased dramatically. This increase is largely due to improvements in isolation procedures and structural analysis. Previous reviews have concentrated on fungal isocoumarins (293,294) and mycotoxic isocoumarins (301). This review lists over 160 naturally occurring isocoumarins. Leading references on isolation, structure...
Isocoumarins have been isolated from a wide variety of microbial, plant and insect sources and have been shown to possess an impressive array of biolo...
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to...
The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer imprin...
The volumes in this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occuring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in this field and provides a comprehensive and up-to-date review of the topic in question. Addressed to...
The volumes in this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprin...
The volumes of this classic series have appeared under the Springer imprint ever since L. Zechmeister founded the series in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists and chemists alike, the series can be used by...
The volumes of this classic series have appeared under the Springer imprint ever since L. Zechmeister founded the series in 1938. The volumes contain ...