In recent years both doctors and patients have become increasingly aware that many essential drugs may induce unfortunate side-effects in susceptible individuals. The kidney is the principal route of excretion for many of these substances and may as a result become involved in pathological processes. Developments in haemodialysis and haemo perfusion may be of value in increasing the rate of excretion of potentially toxic substances but it is essential that the advantages and disadvantages of these techniques are fully appreciated by all with an interest in clinical practice. This book details...
In recent years both doctors and patients have become increasingly aware that many essential drugs may induce unfortunate side-effects in susceptible ...
This book is an edited selection of the papers presented at the International Workshop on VLSI for Artiflcial Intelligence which was held at the University of Oxford in July 1988. Our thanks go to all the contributors and especially to the programme committee for all their hard work. Thanks are also due to the ACM-SIGARCH, the Alvey Directorate, the lEE and the IEEE Computer Society for publicising the event and to Oxford University for their active support. We are particularly grateful to David Cawley and Paula Appleby for coping with the administrative problems. Jose Delgado-Frias Will...
This book is an edited selection of the papers presented at the International Workshop on VLSI for Artiflcial Intelligence which was held at the Unive...
The addition of chemotherapy as an effective means to treat cancer has had a major impact on selected human malignancies. Due to a general inability to dif- ferentiate between normal and neoplastic cells, little selectivity exists in currently used oncolytic drugs. Consequently, significant toxicity to the patient is expected when systemic cancer chemotherapy is chosen as an appropriate therapeutic in- tervention. Much of this toxicity, such as damage to the bone marrow, gastroin- testinal tract, or hair follicles, is predictable based upon the fact that anticancer drugs kill actively...
The addition of chemotherapy as an effective means to treat cancer has had a major impact on selected human malignancies. Due to a general inability t...
Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev er be sure...
Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco logy tex...
In recent years much progress has been made in knowledge and understanding of the biology of cutaneous melanoma. In this respect etiological factors, prognostic factors, antigen expression of melanoma cells, immune response and mechanisms of metastasis formation have to be mentioned. It is the purpose of this book to give a review on fundamental aspects, diagnosis and prognosis, and treatment of cutaneous melanoma and precursor lesions. Moreover, previously unpublished new data are presented. A post-graduate Boerhaave course "Cutaneous Melanoma and Precursor Lesions" was held at Leiden...
In recent years much progress has been made in knowledge and understanding of the biology of cutaneous melanoma. In this respect etiological factors, ...
Proceedings of an interdisciplinary meeting, sponsored by the Commission of the European Communities, as advised by the Committee on Medical and Public Health Research
Proceedings of an interdisciplinary meeting, sponsored by the Commission of the European Communities, as advised by the Committee on Medical and Publi...
The observation in the 1950s that nitrogen mustard and other toxic chemicals could induce antitumor responses in patients with refractory lymphoma initiated a massive search for active chemotherapeutic agents. The initial observations stimulated a search for new chemotherapeutic agents which might have increased antitumor activity with less toxicity for normal tissues. To aid in the search for these new chemicals and to attempt to distinguish among the many toxic chemicals which might be candidates for clinical studies, the National Cancer Institute, the pharmaceutical industry, and the...
The observation in the 1950s that nitrogen mustard and other toxic chemicals could induce antitumor responses in patients with refractory lymphoma ini...
Proceedings of a symposium presented at the University of Southern California, Department of Pathology and the Kenneth J. Norris Cancer Hospital and Research Institute, Los Angeles, U.S.A., November 16-17, 1984
Proceedings of a symposium presented at the University of Southern California, Department of Pathology and the Kenneth J. Norris Cancer Hospital and R...
This year notes two major changes in the annual Detroit Cancer Symposium. The first is our intention of selecting top- ics of broad interest to the cancer community and examining the subject from both a basic laboratory and clinical viewpoint. In this way, the importance of both elements of cancer research are noted and the interplay between them emphasized. Further, we believe that Symposia such as this act to stimulate the basic scientist and clinician to continue their studies with the know- ledge of the impact that each has upon the other and the nec- essary cooperation required to solve...
This year notes two major changes in the annual Detroit Cancer Symposium. The first is our intention of selecting top- ics of broad interest to the ca...
