This year notes two major changes in the annual Detroit Cancer Symposium. The first is our intention of selecting top- ics of broad interest to the cancer community and examining the subject from both a basic laboratory and clinical viewpoint. In this way, the importance of both elements of cancer research are noted and the interplay between them emphasized. Further, we believe that Symposia such as this act to stimulate the basic scientist and clinician to continue their studies with the know- ledge of the impact that each has upon the other and the nec- essary cooperation required to solve...