Drs. Xander Wehrens and Andrew Marks have gathered the collected wisdom of scientists that have devoted their working lives to the study of ryanodine receptors. In this series of brief, but informative, chapters, the contributions progress from the basic gene family and primary structure, through its 3D structure so far, to its regulation and physiology. The book ends with several chapters on mutations in the receptor that causes disease and their role in adaptation to disease. There are interesting new developments in the control of ryanodine receptors by accessory proteins, the latest of...
Drs. Xander Wehrens and Andrew Marks have gathered the collected wisdom of scientists that have devoted their working lives to the study of ryanodi...
Following systematic development of technical aspects and physiological understanding, and clinical applicability of cardiac autonomic testing, this book provides a detailed guide to performing individual autonomic tests in both research and clinical settings. The book is structured in three parts covering the physiological background of cardiac autonomic regulations, description of technology and interpretation of individual autonomic tests, and applicability of the individual tests under various clinical circumstances and in defined populations of patients. The book is intended...
Following systematic development of technical aspects and physiological understanding, and clinical applicability of cardiac autonomic testing, this b...
This volume follows a Specialized Symposium on "Mantle denudation in slow spreading ridges and in ophiolites," held at the XII EUG Meeting in Strasbourg, spring 1993. During the meeting it was felt that the contribu tions to the Symposium justified a volume presenting its main scientific achievements. The present title of the volume shows that the center of inter est has slightly shifted with respect to the initial objective: in order to under stand the processes involved in accretion taking place at oceanic ridges, it is crucial to study the interaction between uppermost mantle and lower...
This volume follows a Specialized Symposium on "Mantle denudation in slow spreading ridges and in ophiolites," held at the XII EUG Meeting in Strasbou...
Cardiac surgery is performed on hundreds of thousands of patients a year, and can have an important beneficial impact on the outcomes of patients with coronary and valvular heart diseases. Despite the favorable recovery of most patients, some will have their post-operative period interrupted by the development of atrial fibrillation, with a host of potential complications including stroke. High risk subgroups may develop atrial fibrillation in more than half of cases, and often despite aggressive prophylactic measures. Treatment of atrial fibrillation and its aftermath can also add days to...
Cardiac surgery is performed on hundreds of thousands of patients a year, and can have an important beneficial impact on the outcomes of patients with...
Noninvasive electrocardiographic monitoring is a fundamental part of cardiology. Depending on continuous improvements and developments of new technologies, these methods are essential for diagnosis and risk stratification of patients. The rapid changes in the capabilities, technologies and diagnostic values of the different methods force us to update our knowledge continuously. This book offers a comprehensive overview of the current state and future developments in the field of noninvasive electrocardiographic monitoring techniques. In addition, related fields such as...
Noninvasive electrocardiographic monitoring is a fundamental part of cardiology. Depending on continuous improvements and developments of new technolo...
Angioplasty has completely transformed the treatment of coronary artery disease and is widely used, with more than 800,000 procedures performed worldwide per year. However, the enthusiasm for angioplasty is shadowed by restenosis, which remains a critical problem after the procedure, resulting in clinical recurrence in over a third of patients. Recently, the mechanisms of restenosis have been completely reappraised with an enriched understanding that the original concept of neointimal hyperplasia may not be accounting for the bulk of the problem. There is a desperate need to heighten...
Angioplasty has completely transformed the treatment of coronary artery disease and is widely used, with more than 800,000 procedures performed worldw...
The VIth World Symposium on Cardiac Pacing in Montreal 1979 opened with a course, meant to be an introduction for newcomers and an updating re fresher and link between the various fields of knowledge needed by experienced persons for cardiac pacing. Invited guest lecturers were selected for their world recognized expertise in the individual subjects. This book is a collection of the various presentations on historical, clinical, electrophysiological and technical aspects of cardiac pacing. Together they cover the fundamentals of cardiac stimulation. We hope that this book may become an...
The VIth World Symposium on Cardiac Pacing in Montreal 1979 opened with a course, meant to be an introduction for newcomers and an updating re fresher...
Accurate diagnosis of arrhythmias is the goal of this volume. Before the clinician can accurately classify the multiple permutations of cardiac rhythm encountered in daily practice, several essential preconditions must be met. At the most basic level, the clinician must know the diagnostic criteria for each rhythm. Without a clear understanding of these criteria, an accurate differential diagnosis is impossible, and without accurate diagnosis, correct intervention is a mere matter of chance. A second precondition of accurate rhythm diagnosis is an understanding of the mechanism of...
Accurate diagnosis of arrhythmias is the goal of this volume. Before the clinician can accurately classify the multiple permutations of cardiac rhythm...
This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work in which Professor Yung E Earm, at Seoul National University, had been involved both in my laboratory in Oxford and in his own laboratory in Seoul concerning the possible role of certain amino acids, like taurine that are strongly concentrated by the cells of the heart, and the relationship between such acids and membrane ionic currents. The first obvious question was whether it is possible to identify the transport mechanisms involved for taurine and...
This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work in which ...
The field of molecular genetics has rapidly expanded and is becoming increasingly important in the area of cardiac electrophysiology. The genetic basis of cardiac conduction disturbances and arrhythmogenesis is now recognized as a critical factor in disease pathology. Inherited structural and electrical heart diseases are being elucidated using molecular biological approaches, with differentiation of gene-specific diagnosis, prognostication, and therapeutics. Unique genetically-engineered animal models of hereditary arrhythmias and heart disease are being developed and utilized for detailed...
The field of molecular genetics has rapidly expanded and is becoming increasingly important in the area of cardiac electrophysiology. The genetic basi...
