The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, is an im portant responsibility of physicians. The history of medicine is characterized by the authoritarianisms of teachers and of organizations giving way to the clinical experience of physicians; authoritarian dictum was replaced by case report and then by case series. As physicians learned to substitute the analysis of data for the inconsistencies of dictums and anecdotes, the problems of the case series as an investigative tool became more...
The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, i...
Although soft tissue sarcomas are rare tumors, representing only 1 % of all malignant tumors in adults, they remain a challenge to all disciplines in medical treatment and research. Apart from research in all fields of treatment, soft tissue sarcomas are also encountered in several forms of combined modality treatment. Since the appearance of the first volume on soft tissue sarcomas in this series (Soft Tissue Sarcomas, Laurence H. Baker, ed., Martinus Nijhoff Publishers, 1983), a large amount of data has emerged from preclinical as well as clinical in- vestigations. The present volume...
Although soft tissue sarcomas are rare tumors, representing only 1 % of all malignant tumors in adults, they remain a challenge to all disciplines in ...
During the course of editing 'Supportive Care in Cancer Therapy' (Martin us Nijhoff Publishers, 1983), it become apparent that several topics would have to await a second volume. Furthermore, development of new informa- tion and evolution of ideas continues. This volume continues the intent of the first to present reviews of issues relating to supportive care, and to identify areas where further definition and further research is needed. The physician reading this volume will find the contents though-provok- ing. In addition to reviews authored by physicians, there are chapters authored by...
During the course of editing 'Supportive Care in Cancer Therapy' (Martin us Nijhoff Publishers, 1983), it become apparent that several topics would ha...
A multidisciplinary approach to the problems related to the diagnosis, treat ment, and rehabilitation of patients with oral cancer and precancer is reflected in the various specialties of the authors who contributed to this book. Today, patients with tumors of the oral cavity are dealt with preferably by a team of specialists who have been properly trained in the field of oncology, who have learned to appreciate each other's knowledge and experience, and who are able to operate as an integrated team. This book is intended for use by every physician and dentist involved in the diagnosis and...
A multidisciplinary approach to the problems related to the diagnosis, treat ment, and rehabilitation of patients with oral cancer and precancer is re...
Where do you begin to look for a recent, authoritative article on the of a particular malignancy? The few general onco- diagnosis or management logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi- nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be...
Where do you begin to look for a recent, authoritative article on the of a particular malignancy? The few general onco- diagnosis or management logy t...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology tex...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear spo- radically, and the reader can never be sure...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology tex...
Patients with a variety of tumors present to the physician because of clinical manifestations of hormones secreted in excess. This phenomenon attracted the investigative interest of such pioneers as Harvey Cushing who recognized that pituitary tumors may cause acromegaly and Charles Mayo who associated hyper tension with adrenal medullary neoplasms. Current int rest in endocrine-related tumors has intensified because of the explosive development of newer methodol ogy for their study. Specific measurements of secretory products, hybridization assays to identify products of genomic translation...
Patients with a variety of tumors present to the physician because of clinical manifestations of hormones secreted in excess. This phenomenon attracte...
Lung cancer remains an extremely difficult neoplasm to treat effectively. A large part of our lack of success in dealing with these patients is related to our empiric therapeutic attempts. Slowly our basic understanding of the lung cancers is improving and techniques are becoming available to allow us to better understand the biology of these neoplasms. This volume reviews several areas of interest in regard to the biologic behavior and characteris- of lung cancer. tics Chapters deal with the in vitro growth of small cell lung cancer, the inves- tigation of growth factors in human lung...
Lung cancer remains an extremely difficult neoplasm to treat effectively. A large part of our lack of success in dealing with these patients is relate...