Concepts, Clinical Developments, and Therapeutic Advances in Cancer Chemotherapy

ISBN-13: 9780898388756 / Angielski / Twarda / 1987 / 268 str.

F. Ed Muggia; Franco M. Muggia

Opis

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung can cer, genitourinary cancer, pediatric oncology, etc. Second, by asking emi nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Spis treści

I. Concepts.- 1. DNA filter elution methods in anticancer drug development.- 2. Intraperitoneal chomotherapy: Principles and results of clinical trials.- II. New Drugs and New Clinical Investigation.- 3. Metabolites of tiazofurin as mediators of its biochemicaland pharmacologic effects..- 4. Extragonadal and central nervous system germ cell tumors:A review of diagnostic and therapeutic strategies.- 5. Role of preclinical pharmacology in phase I clinical trials:Considerations of schedule-dependence.- 6. Interferon: Current concepts of mechanisms of action.- 7. Acivicin: A new antimetabolite.- III. Specific Therapeutic Landmarks.- 8. Chemotherapy for malignant intracranial tumors.- 9. New antiviral compounds and impact in management of neoplastic disease and AIDS.- 10. The clinical horizon of deoxycoformycin.