In human solid cancer, the lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients. Recent developments in the sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to define the first draining or SLN to which the cancer may have metastasized. The underlying thesis in solid cancer biology is that metastasis generally starts in an orderly progression, spreading through the lymphatic channels to the SLN in the nearest LN basin. Thus, the logical approach is to harvest that specific SLN...
In human solid cancer, the lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients. Recent developme...
Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It illustrates the benefit of the principles of geriatrics in the management of cancer in the older individual.
This volume provides a frame of reference for practicioners of any specialties involved in the management of older patients and for oncologists involved in the management of cancer of older individuals. It is a source for basic and clinical...
Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer...
Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient with leptomeningeal cancer with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies.
Leptomeningeal Metastases is intended to provide the reader with an overview of the state-of-the-art therapy for the cancer patient w...
Dramatic advances have occurred over the last few years in the research field of cancer biology. There has been a constant accumulation of important new information, resulting in a gradual transformation on the perceptions that exist among scientists regarding mechanisms by which the malignant phenotype develops. The recent developments in cancer research have also had a substantial impact in efforts towards the development of new cancer therapies. One of the most explosive and rapidly advancing research areas has been the area of cytokines and cancer. Many perceptions have changed from the...
Dramatic advances have occurred over the last few years in the research field of cancer biology. There has been a constant accumulation of important n...
This volume outlines patient care from diagnosis through various treatments for thyroid cancer patients. It serves as a state-of-the-art reference for clinicians providing comprehensive information on the scope of this disease, including surgery, nuclear medicine treatments, recurrence and metastases. The reference information is included for both physicians and thyroid cancer patients.
This volume outlines patient care from diagnosis through various treatments for thyroid cancer patients. It serves as a state-of-the-art reference for...
A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased...
A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection...
In recent years a dramatic increase in knowledge of the biology of the lymphomas has been accompanied by the emergence of new treatments offering improvements in efficacy and reduction in toxicity. In this volume an internationally recognized group of experts review relevant aspects of the biology, diagnosis and management, with particular emphasis on the emerging data available for this disease.
In recent years a dramatic increase in knowledge of the biology of the lymphomas has been accompanied by the emergence of new treatments offering i...
Clinical trials remain the most important vehicle for improving the care of cancer patients. This text presents the fundamental components and challenges involving clinical investigations. Leading experts discuss the critical issues covering the spectrum of important topics from planning to application.
Clinical trials remain the most important vehicle for improving the care of cancer patients. This text presents the fundamental components and chal...
AIDS is a major worldwide health care crisis. One of the most important aspects of the disease is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. Of particular note are viral-associated cancers.
Aids-Associated Viral Oncogenesis will specifically address viral-induced human cancers. Topics will cover the viral associated cancers observed in the AIDS population, specific treatment required in this special population, and molecular biology of the causative viral agents.
AIDS is a major worldwide health care crisis. One of the most important aspects of the disease is the loss of protective immune function in the inf...
Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of progression via the lymphatic network, while 20% of the time systemic metastasis occurs, bypassing the lymphatic system. During the past two decades, significant progress has been achieved in understanding the anatomical, functional, cellular and molecular aspects of the lymphovascular system and the metastasis process.
. Molecular imaging advances help to localize early cancers more precisely.
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Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis th...