Aids-Associated Viral Oncogenesis

ISBN-13: 9780387468044 / Angielski / Twarda / 2007 / 270 str.

Craig Meyers

Opis

AIDS is a major worldwide health care crisis. One of the most important aspects of the disease is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. Of particular note are viral-associated cancers. Aids-Associated Viral Oncogenesis will specifically address viral-induced human cancers. Topics will cover the viral associated cancers observed in the AIDS population, specific treatment required in this special population, and molecular biology of the causative viral agents.

Recenzje

From the reviews:

"Almost a quarter of a century has passed since the human immunodeficiency virus (HIV) was identified. ... The availability of a summary of this research and its clinical applications in a slim and eminently readable volume is therefore welcome, particularly as it relates to Kaposi's sarcoma, lymphoma, squamouscell neoplasia, and genital dysplasia. ... I found myself turning the pages with increasing excitement as the story of viruses and cancer unfolded." (Jonathan Said, New England Journal of Medicine, January, 2008)

Spis treści

Overview.- Aids Malignancies.- Molecular Biology of KSHV in Relation to AIDS-Associated Oncogenesis.- KSHV-Associated Disease in the AIDS Patient.- Molecular Biology of EBV in Relationship to AIDS-Associated Oncogenesis.- EBV-Associated Diseases in the AIDS Patient.- Human Papillomavirus Infection and Disease in the HIV+ Individual.- Polyomavirus SV40 and AIDS-Related Systemic Non-Hodgkin's Lymphoma.- HIV–HBV and HIV–HCV Coinfection and Liver Cancer Development.

Blurb

AIDS-associated viral oncology is a significant healthcare problem. Since the identification of human immunodeficiency virus (HIV)-associated acquired immune disease syndrome (AIDS), the role of viruses in human cancers has become acutely apparent over the past twenty years. The understanding and treatment of AIDS-associated cancers has become a major concern among healthcare organizations. Human cancers that were once rare in the population have now become common within the HIV infected population.

Experts share their collective knowledge and examine the clinical and biological aspects, including viruses well established in their roles, as well as emerging new viruses. This volume will be a resource for both members of the scientific and healthcare community and active researchers in this field.

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"Human immunodeficiency virus (HIV) - associated acquired immune disease syndrome (AIDS) places individuals at increased risk for virally mediated cancers. This text addresses the clinical and biological aspects of this topic. Distinguished investigators in the field present a comprehensive overview with relevance to laboratory scientists and practicing clinicians."

Steven T. Rosen, M.D.

Series Editor