This book is devoted to the investigation of a rather prevalent process in nature: interaction of atoms with electromagnetic radiation. Primary attention is given to the low and intermediate photon energy region, from tens to hundreds of electron-volts. It is in this region that the probability of photon absorption and photoionization is largest. Data in this energy region are very interesting and useful in astrophysics and plasma physics, solid-state physics and quantum electronics, and in a number of other branches of science and technical applications. Formulae for hydrogen atom...

The initial conceptualization of this book was much more narrow than the final product that has emerged. I started out believing that it would be enlightening to have a group of acknowledged rational-emotive therapy (RET) expert practitioners with well-established literary credentials write about how they approach the problem of modifying dient irrationality. Many RET practitioners of all levels of experience are, on the one hand, enamored of the economy, the precision, and the accuracy of psychological insight that RET theory offers, but they are, on the other hand, equally frustrated by...

This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar keted or are under clinical testing. In previous volumes of this series, funda mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise. The way from theory to practice isnot alwaysobvious and straightforward. There isa need for practical examples of how the principles and theories are put into use, specificallyin the development of a pharmaceutical product. It is...

Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency...

Blood Cell Biochemistry was initially conceived as part of the Plenum series Subcellular Biochemistry, from which it has developed into a separate series. The present volume is devoted primarily to contributions on megakaryocytes and platelets and, to a lesser extent, to macrophages and eosinophils. The book does not attempt a rigorous or total coverage of the particular topics; it represents the areas of current scientific activity and interest that were selected by the editor at the commencement of this project. In general, the approach has been similar to that adopted for Volume 1 of the...

This third volume follows the pattern of the series by containing specialist reviews of topics within the field. Thirteen chapters address various aspects of white blood cell biochemistry, among them: molecular markers of hemopoietic precursor cells; cell surface markers in leukemia and lymphoma; th

The information will be very useful for the entrepreneur who first sets up a materials processing plant on Jupiter, of course, but until then it allows scientists using centrifuges to discover the influence of acceleration and convection on materials processing and to produce unique and improved mat

This, the third volume of the Blood Cell Biochemistry series, follows the pattern estab- lished in the two previous volumes by containing up-to-date specialist reviews of topics of current interest within the field of study defined by the subtitle. Thus, the topics included can be loosely classified under the broad subtitle "Lymphocytes and Granulocytes," but this does not indicate the full scope of content, scientific interest, and emphasis of the present volume. The opening chapter, by Antonio Bonati, surveys the currently available bio- chemical, immunological, and molecular markers of...

Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency...

Historically, the field of hematopoietic growth factor research began with the work of Carnot and Deflandre-in 1906 they suggested that the rate of erythropoiesis is regulated by a humoral factor found in the blood, namely, erythropoietin. From this comparatively early start, accelerating progress has been made in erythropoietin research, which demon- strates the general trends in this field of study. Erythropoietin was purified to homogeneity by 1977 (from enormous quantities of urine from aplastic anemia patients). Subsequently, the gene for erythropoietin has been cloned (1985), and...