Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis.
Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It...
Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has att...
Profound mortality rates, due to cardiovascular disease, are a worldwide problem. Cardiovascular disease results from complications of a silent and chronic arterial disease: atherosclerosis. The challenge for the practitioner is adapting diagnostic and therapeutic responses to prevent this common and complex disease. Dyslipidemia, are disorders of the metabolism of soluble transporters of lipids in extracellular spaces of the human body (including blood), called lipoproteins. They are major cardiovascular risk factors, causally related with atherosclerosis and are themselves...
Profound mortality rates, due to cardiovascular disease, are a worldwide problem. Cardiovascular disease results from complications of a silent and ch...
Since it was introduced less than 100 years ago, analysis of the circulatory response to exercise as a measure of cardiac function has undergone remarkable development. Most recently this approach has incorporated the burgeoning technology of the last half of the 20th century to meet the physiological and diagnostic needs of scientist and clinicians. The ease of administration, economy and abundant data that characterize exercise testing for its relative staying power as the most frequently utilized noninvasive method of cardiovascular evaluation. The basic modalities of exercise...
Since it was introduced less than 100 years ago, analysis of the circulatory response to exercise as a measure of cardiac function has undergone remar...
Scrambling Techniques for CDMA Communications addresses spreading, scrambling, and synchronization techniques for use in inter-cell synchronous and asynchronous CDMA systems, including the IMT-2000. It provides fundamental background material for sequences and shift register generators, and demonstrates various acquisition techniques in primitive, advanced levels, and in the third generation (3G) DS/CDMA cellular systems. In addition, it introduces the novel acquisition techniques DSA (Distributed Sample Acquisition) and CDMA (Correlation-aided DSA) that enable rapid and robust...
Scrambling Techniques for CDMA Communications addresses spreading, scrambling, and synchronization techniques for use in inter-cell synchrono...
Cardiac Cellular Electrophysiology is intended for the clinical cardiologist who wishes to refresh or deepen his understanding of the cellular basis of cardiac electrophysiology, for researchers interested in the basis of the electrical activity of the heart, such as clinical investigators, physiologists or pharmacologists, for teachers in physiology, pharmacology and other biomedical studies, and for medical students from graduate to postgraduate level. Cardiac Cellular Electrophysiology starts with a primer of basic electrophysiology, the cardiac action potential and...
Cardiac Cellular Electrophysiology is intended for the clinical cardiologist who wishes to refresh or deepen his understanding of the cellula...
Cardiac Ischemia: From Injury to Protection has been divided into six parts. The first part describes the differences between hypoxia and ischemia, animal models, the effects of ischemia on myocardial function and metabolism, and the electrophysiological consequences of ischemia. The second part deals with the mechanisms of cardiomyocyte death in ischemia, structural aspects of irreversible ischemic injury, necrosis and apoptosis of cardiac cells, the role of calcium, and the concept of calcium antagonism. The third chapter is a brief description of reperfusion injury, its clinical...
Cardiac Ischemia: From Injury to Protection has been divided into six parts. The first part describes the differences between hypoxia and isc...
Apoptosis or programmed cell death is increasingly considered to be a major factor in the development and progression of cardiovascular disease. In patients with heart failure the activation of apoptosis may result in the loss of irreplaceable cardiac myocytes promoting the clinical course of the syndrome. Moreover, in the coronary arteries inflammation and apoptosis may weaken critical structures of the vessel wall leading to plaque rupture and, subsequently, to myocardial infarction. Given these deleterious consequences, it seems almost paradoxical that programmed cell death is an active...
Apoptosis or programmed cell death is increasingly considered to be a major factor in the development and progression of cardiovascular disease. In pa...
ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current understanding of the chemistry and biology of ATP specifically in the cardiomyocyte is presented. New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac...
ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in o...
Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own...
Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and im...
Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student interested in learning how molecular genetics is now being applied to prevention and treatment of heart diseases, from DNA tests to pharmacogenomics and gene-based therapeutics. The volume, written in a plain language, contains detailed figures. A rich glossary, three appendices, many references and several URLs provide additional sources of information.
Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student in...
