Oral-based diagnostics have the potential to detect systemic disease and evidence of exposure to various harmful substances, as well as provide biomarkers of health and disease status. Integration of novel approaches to oral-based diagnostics is expanding to include genomics, proteomics, bioinformatics, and nanotechnology.
Improved technologies for diagnostics are resulting in more -user-friendly- methods. Efforts to translate bench assays to commercial products in the area of oral diagnostics have increased recently, as witnessed by the appearance of several new oral-based diagnostic...
Oral-based diagnostics have the potential to detect systemic disease and evidence of exposure to various harmful substances, as well as provide biomar...
Drawing upon the expertise of a cadre of scholars and practitioners, this book has four parts: (1) conceptualizing violence and exploitation against females, (2) violence against girls and female adolescents, (3) violence against women, and (4) cultural and international perspectives on violence against women.
Contributors place violence against women and girls within a variety of cultural and religious perspectives and also present theories of violence, the role of stereotyping, and the effect of violence in the larger community. The recent emergence of cyber violence, particularly...
Drawing upon the expertise of a cadre of scholars and practitioners, this book has four parts: (1) conceptualizing violence and exploitation against f...
Biological aging and interventionary strategies are investigated with the eventual goal of extending healthy human lifespan and minimizing the incidence of diseases associated with aging.
Biogerontologists, evolutionary biologists, biodemographers, scientists in related basic research, clinicians, and dieticians came together in Istanbul, Turkey, to share their research and discuss the latest developments in this rapidly advancing field.
This volume presents chapters representative of the highlights of the meeting, including contributions in the following areas: (1)...
Biological aging and interventionary strategies are investigated with the eventual goal of extending healthy human lifespan and minimizing the inciden...
Inflammatory bowel disease (IBD), which encompasses both Crohn's disease and ulcerative colitis, is a chronically relapsing intestinal disorder that is characterized by diarrhea and abdominal pain.
The incidence of IBD is increasing worldwide. Although some major advances have been made in recent years, the pathogenesis of the disease still remains obscure. As currently understood, a combination of genetic alterations and immunological disturbances causing an interaction of the enteric microflora with the underlying mucosa and a disrupted barrier function may be crucial for the...
Inflammatory bowel disease (IBD), which encompasses both Crohn's disease and ulcerative colitis, is a chronically relapsing intestinal disorder that i...
Although the peoples of all continents and cultures have been using different kinds of natural products for centuries, their mechanisms of action are poorly understood. Interestingly, most of these products -work, - and paradoxically we are witnessing a great limitation of existing pharmacological targets and agents for various new diseases, such as HIV, as well as those that affect the growing aged population worldwide.
This volume presents research focused on the molecular basis of action of different natural products and their applications to various diseases, including cancer,...
Although the peoples of all continents and cultures have been using different kinds of natural products for centuries, their mechanisms of action are ...
Biomedical research on human subjects is notoriously difficult because of the difficulties in controlling the variables, locating a large enough sample size, and managing the ethical issues that have to be considered for every experiment. This volume contains contributions from scientists who have received grants from the Dana Foundation, and their work in the complex and diverse field of human immunology is notable for both its breadth and its depth.
Patient-based research in the areas of cancer, infectious disease, allergy, inflammation, and autoimmunity are summarized. It is...
Biomedical research on human subjects is notoriously difficult because of the difficulties in controlling the variables, locating a large enough sampl...
When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance cell survival or remove irreparably injured cells. Following injury, cells attempt to seal breaks in their membranes, chaperone removal or refolding of altered proteins, repair damaged DNA, or if necessary commit to programmed cell death.
When cell injury is too extensive to permit reparative responses, acute cellular necrosis or apoptosis can result. Understanding injury at the subcellular organelle and molecular levels is essential...
When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance...
Virtually every aspect of mitochondrial research and medicine is addressed in this volume, including mitochondrial function and dysfunction, free radical biology relevant to mitochondrial dysfunction, the role of mitochondria in apoptosis, and abnormal signaling processes and disease mechanisms associated with aging, mtDNA mutations, or mitochondrial damage.
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Virtually every aspect of mitochondrial research and medicine is addressed in this volume, including mitochondrial function and dysfunction, free radi...
Exciting papers by leading researchers are integrated in this volume with presentations having direct clinical relevance: thus, the latest scientific advances in aging research are coupled with reports on how these advances are being applied to longevity medicine.
Topics include oxidative stress, genetic/biochemical mechanisms, hormone therapy, nutrition, fitness, and exercise, all as they pertain to aging.
In exploring the links between the latest basic gerontological research and the practice of longevity medicine, the current challenges faced by both scientists and...
Exciting papers by leading researchers are integrated in this volume with presentations having direct clinical relevance: thus, the latest scientific ...
The body of research on the process of human aging has grown considerably in recent years, and the reports presented here explore a full range of approaches to this research, from the molecular and genetic to the cellular and organismic levels.
The contributing scientists identify the processes of aging and find functional and mechanistic approaches that may delay, prevent, or arrest the progress of aging and those ailments generally linked to senescence, such as metabolic, cardiovascular, and autoimmune diseases. The investigation of various approaches to the prevention of aging...
The body of research on the process of human aging has grown considerably in recent years, and the reports presented here explore a full range of appr...
