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Sequence and Genome Analysis: Methods and Applications provides a comprehensive review and discussion on the key problems in computational biology. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. This book is organized as follows: Chapter 1 discusses Photonic DNA computing, which denotes the nano-scale information technology employing photonics and DNA. Because the activity of a living body is regulated by a variety of bio-molecules such as DNAs, RNAs, and proteins,...