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In spite of the availability of multi-bullet effective chemotherapy and BCG vaccine, tuberculosis is leading infectious killer globally. TB kills about 2 million people per year. At present, approximately one-third of the world's population is infected with Mycobacterium tuberculosis and new infections occur @ one individual per second. There are several reasons that are responsible for such havoc despite the multidrug regimens. These include drug resistance, development of latency, patient non-compliance, delay in diagnosis, variable efficacy of BCG vaccine and co-infection with HIV etc.The...

This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional formulations used to affect therapy or treatment of a disease state. The authors examine the potential uses of dendrimers, which have proven their capabilities in local/systemic drug delivery, physical stabilization of the drug, solubility enhancement of the poorly soluble drugs, and gene delivery.