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Discovery of penicillin enlighten humanity with its miraculous results in curing bacterial infection. During the time users forgot the words of Alexander Fleming regarding alarming the antibiotic overuse in 1945 with the remarks It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body. In a very short time evidences of penicillin- resistant S. aureus emerged in 1942. Thus, microbes proved to be smarter than us and it is an ongoing phenomena. The...