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The growing level of antimicrobial resistance has become a severe health problem worldwide so there is a need to design new heterocyclic drug candidates. Therefore, it is now the highest priority for researchers to discover new antimicrobial hybrid molecules having a combination of two heterocyclic rings having different modes of action to solve this serious problem. We have presented an In-silico based design of some novel thiazole incorporating pyrimidine derivatives as potential antimicrobial scaffolds and studying their synergistic effect in this book. The valuable information provided in...

Communication plays a vital role in breaking down barriers between the patient and dentist, and in strengthening the treatment alliance. Regarding the sucess of use, care and maintenance of the prosthesis, dentist must know their patients. They can do this by considering important episodes in their patient's lives, by knowing problems or difficulties their patients encounter and by recognising their patient's apprehensiveness about dental treatment. Dentist must be proficient in their communication skills. They must encourage their patients to ventilate their feelings, thoughts, worries and...