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70 years after the discovery of secretory neurons, internationally leading experts gathered to discuss the latest developments in neuropeptide research and endocrinology, concentrating on the molecular, cellular, supracellular and systemic aspects. A variety of neuropeptidergic systems are considered under comparative and evolutionary aspects.

An updated view of structure, cell and molecular biology of the vertebrate pineal organ, which is the source of the "timing hormone", melatonin. Areas addressed include: phylogenetic development and gross anatomy of the pineal complex; biology and innervation; and pineal transcription factors.

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance.