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The idea that we are one step from calamity is as old as history itself. Every step on the road of progress has been countered by those who think that we should keep to a primitive lifestyle that they claim is compatible with nature. But despite the fact they've been proved wrong, the pessimists are undeterred by their abysmal record. Today, industrialization, genetically modified crops, scientific medicine, nuclear power, and the car are held up as harbingers of doom. Politicians and pressure groups play on this same basic fear. They scare us with tales of an inevitable global warming...

Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of...