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In the last 50 years molecular biology was dominated by the exploration of proteins and nucleic acids. Beside their role in energy metabolism, oligos- charides, which represent thethirdclass ofbiomacromolecules, have received less attention. Today it is well established that oligosaccharides are involved in many important biologicalregulation and recognition processes fromp- tein folding to cell cell communication. Glycosylation of proteins is the most complexformofco-andposttranslationalmodi?cation. Thedeterminationof structure-function relationships, however, remains dif?cult due to the...

Contents: C. Haase, O. Seitz: Chemical Synthesis of Glycopeptides.-D.A. Thayer, C.-H. Wong: Enzymatic Synthesis of Glycopeptides and Glycoproteins.- D. Specker, V. Wittmann: Synthesis and Application of Glycopeptide and Glycoprotein Mimetics.-J.D. Warren, X. Geng, S.J. Danishefsky: Synthetic Glycopeptide-Based Vaccines.-F. Wolter, S. Schoof, R.D. Sussmuth: Synopsis of Structural, Biosynthetic, and Chemical Aspects of Glycopeptide Antibiotics.- B. Meyer, H. Moller: Conformation of Glycopeptides and Glycoproteins