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Seizure is a paroxysmal event due to abnormal, excessive, hypersynchronous discharges from an aggregate of central nervous system neurons. Zinc sulfate, carvedilol and amlodipine have anticonvulsant effects through blocking sodium, calcium, and neurotransmitter (glutamate) receptors, and through their action on excitatory and inhibitory neurotransmitter levels, ion levels and cellular oxidative stress.

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizures can occur due to many different cellular or biochemical changes such as alterations in ion channel function, neurotransmitter level (excitatory and inhibitory), neurotransmitter receptor function, energy metabolism, electrolytes level and oxidative stress. This study investigate that atorvastatin and L-carnitine had antiepileptic effects through their action on cholesterol biosynthesis, free radicals, electrolytes and glutamate receptors

Epilepsy is a chronic neurological disorder characterized by disturbances of electrical activity in the brain and recurrent unprovoked seizures. This abnormal electrical activity may result in a variety of events, including loss of consciousness, abnormal movements, atypical or odd behavior, or distorted perceptions that are of limited duration. Verapamil and olanzapine possess antiepileptic effects through their action on oxidative stress, electrolyte levels and neurotransmitter receptors.